Biotechnology Engineering Interview Questions and Answers
Question - 21 : - What Is The Reaction-taking Place When H2 Receptor Binds To Mast Cells And Basophils?
Answer - 21 : -
When H2 binds to mast cells and basophils it suppresses degranulation.
Question - 22 : - Explain In Brief About Leukotrienes And Prostaglandins?
Answer - 22 : -
Leukotrienes and prostaglandins are formed only when the mast cell undergo degranulation and enzymatic break down of phospholipids in the plasma membrane.
The effects produced by them are more pronounced and long lasting than histamine. Leukotrienes mediate mucous production and bronchoconstriction. Prostaglandin D2 causes bronchoconstriction.
Question - 23 : - Explain In Brief About Cytokines?
Answer - 23 : -
Cytokines activate inflammatory cells such as neutrophils and eosnophils.IL-5 is important in activation of eosnophils, IL-4 increases IgE production by B-cells. IL-4, Il-5, IL-6, TNF-a has been secreted by human mast cells.
Question - 24 : - What Is Atopic Dermatitis?
Answer - 24 : -
Atopic dermatitis is an inflammatory skin disease. This disease is observed frequently in young children. There will be skin eruptions.
Question - 25 : - What Is Erythroblastosis Fetalis?
Answer - 25 : -
It is a hemolytic disease, which develops in newborn. Maternal IgG antibodies cross the placenta and destroy the red bleed cells. This develops when an Rh+ expresses an Rh antigen on blood cells that the mother does not express.
Question - 26 : - What Is A Rhogam?
Answer - 26 : -
Is an antibody that binds to any of the blood cells, enter the mother’s blood circulation, and facilitate their clearance by activation of B-cells and memory cell production.
Question - 27 : - What Is Type Iii Hypersensitivity?
Answer - 27 : -
It is immune complex mediated hypersensitivity. Typical manifestations include rheumatoid arthritis, serum sickness, necrotizing etc.
Question - 28 : - Name Some Infectious Diseases?
Answer - 28 : -
Some of the Infectious diseases are Malaria, meningitis, trypanosomiasis, hepatitis etc…
Question - 29 : - Name Some Autoimmune Diseases?
Answer - 29 : -
Rheumatoid arthritis, systemic lupus erythematosus, good pasture’s syndrome
Question - 30 : - How Many Types Of Hypersensitive Reactions Are There?
Answer - 30 : -
There are four types of hypersensitive reactions, they are:
Type I hypersensitive reaction
Type II hypersensitive reaction
Type III hypersensitive reaction
Type IV hypersensitive reaction