Biotechnology Engineering Interview Questions and Answers
Question - 11 : - Name Some Common Allergens Associated With Type-i Hypersensitivity?
Answer - 11 : -
Penicillin, sulfonamide, eggs, milk, dust mites, animal air, vaccines etc.
Question - 12 : - What Are Allergens?
Answer - 12 : -
Allergens are non-parasitic antigens. They are capable of stimulating hypersensitive reactions in allergy conditions in an individual.
Question - 13 : - Which Type Of Immunoglobulin Level Will Increase When An Individual Is Exposed To A Parasite?
Answer - 13 : -
Serum IgE levels will increase and remain until the parasite is washed out from the body.
Question - 14 : - What Is Type Iv Hypersensitivity?
Answer - 14 : -
It is cell-mediated hypersensitivity. Typical manifestations include graft rejection, dermatitis etc.
Question - 15 : - What Is Serum Sickness?
Answer - 15 : -
When an individual is exposed to foreign serum antigen then a combination of symptoms are produced which is called as serum sickness.
Question - 16 : - Give Some Symptoms Of Serum Sickness?
Answer - 16 : -
Symptoms include fever, weakness, rashes, with erythema and edema. Serum sickness depends on the immune complexes formed and the size of the complexes.
Question - 17 : - What Are Primary Mediators?
Answer - 17 : -
Primary mediators are those, which are produced before degranulation. These primary mediators are stored in granules. Some of the primary mediators are histamine, heparin, proteases etc.
Question - 18 : - What Are Secondary Mediators?
Answer - 18 : -
Secondary mediators are produced after target cell activation or released by the break down of phospholipids membrane during the process of degarnulation. Some of the secondary mediators are leukotrienes, various cytokines, prostaglandins etc
Question - 19 : - Explain In Brief About Histamine?
Answer - 19 : -
It is formed by the decarboxylation of amino acid histidine. It accounts for 10% of granule weight. This histamine binds to specific receptors on various target cells.
Question - 20 : - How Many Types Of Histamine Receptors Are There And What Are They?
Answer - 20 : -
There are three types of histamine receptors. They are H1, H2 and H3.They has different tissue distributions.